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issues with sensitivity due to kinetic discrepancies (e.g., confounding stoichiometry in ORAC resulting from area-under-the-curve integration) and inherent probe limitations (e.g., the pH dependency of fluorescein)

This process may initiate the inappropriate incorporation of selenocysteine (SeCys) and selenomethionine (SeMet) into proteins, as well as impair their function, which may in turn lead to the development of oxidative stress, i.e., a state in which the oxidizing potential increases to the level that threatens the stability of cellular structures [14]

W.JaenischR.et al (2007)

Only 2 pounds in two weeks with diet and daily exercise