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That said, signs or symptoms that you may be low in vitamin B12 include: fatigue pale skin headaches symptoms of depression stomach issues difficulty focusing or concentrating pain or inflammation in the mouth or on the tongue burning or pins and needles feeling in your hands or feet muscle cramps vision changes Learn more: Signs and symptoms of B12 deficiency

Safe storage within the temperature of -20C to 4C (4F to 39F) is recommended

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In order to work effectively, the NOS enzyme requires a cofactor molecule called BH4 ( tetrahydrobiopterin )