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Risk factors include genetics, repetitive strain, obesity, smoking, diabetes, and a sedentary lifestyle.Why It Happens Causes (Etiology and Pathophysiology)The main cause of degenerative disc disease is loss of hydration in the discs, which makes them less resilient

The treatments effectiveness is closely tied to your commitment to a healthy diet and regular exercise

In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial