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10.1038/nrc.2016.71 6 AmaryM

Oxidative stress in Portuguese children with Down syndrome Background - Individuals with Down syndrome have an accelerated process of ageing which is thought to be associated with oxidative stress

A single temperature excursion above 25C for more than 2 hours renders reconstituted peptides unusable

EV2G), a ferroptosis inducer that inhibits the cystine/glutamate antiporter (system XC ) known to provide cystine (i.e., the oxidized form of cysteine) required for glutathione synthesis (Dixon et al, 2012)