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Elevated serum cholesterol, liver damage, systemic inflammation, and hypoxic conditions can increase XO secretion via hepatic and other visceral pathways into the bloodstream and bind to the endothelial cell surface, initiating the overproduction of superoxide [77]

Mechanism L-Carnitine works by enabling the body to use fat as fuel more efficiently during exercise

Mice were maintained in a specific pathogen-free environment under standard conditions (221C, 55% humidity and 12/12-h light/dark cycle) with free access to food and water