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Front Physiol 11:566506

Nitric oxide (NO) is a free radical gas molecule produced endogenously from L-arginine, oxygen, and NADPH by an enzyme nitric oxide synthase (NOS) [139]

Adding cagrilintide brings a fourth

Summary Keywords ferroptosis, angiogenesis, metabolic reprogramming, extracellular vesicles, oxidative stress, tumor microenvironment Citation Tatode A, Chaudhary AA, Qutub M, Trivedi R, Umekar M, Ali MAM and Premchandani T (2025) Dissecting the opposing regulatory functions of endogenous nitric oxide production in colorectal cancer initiation, adaptive immune response alterations, and ferroptosis execution