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[2] Histamine Intolerance HIT According to World Allergy Organization, histamine intolerance (HIT) is classified as a non-allergic food hypersensitivity [1,2] and can be defined as a disorder where reduced histamine degradation capacity in the intestines leads to the appearance of adverse symptoms possibly caused by impaired diamine oxidase (DAO) activity [1,3]

A large systematic review did not find a significant reduction in implantation rates (RR = 0.83, 95% CI: 0.681.01, P = 0.07), clinical pregnancy rates (RR = 0.94, 95% CI: 0.831.07, P = 0.35) or livebirth rates (RR = 0.92, 95% CI: 0.831.02, P = 0.10) in mild/moderate endometriosis, although fertilization rates were significantly lower (RR 0.93

In exploring this question, we considered multiple targeting ligands that might deliver an attached bone anabolic agent specifically to fracture surfaces following parenteral administration

Mutlib AE, Goosen TC, Bauman JN, Williams JA, Kulkarni S, Kostrubsky S: Kinetics of acetaminopen glucuronidation by UDP-Glucuronosyltransferases 1A1, 1A6, 1A9, and 2B15