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An antisense oligonucleotide-loaded blood-brain barrier penetrable nanoparticle mediating recruitment of endogenous neural stem cells for the treatment of Parkinsons disease

The total reaction mixture consisting of 1.5 ml sodium phosphate buffer (0.1 M, pH 7.5) and PVP (1% w/v) L-methionine (13 mM), enzyme extract (0.1 ml) with same amounts of NBT solution (2.25 mM), riboflavin (60 M), Na 2 CO 3 (1 M), EDTA (3 mM) and double-distilled water (1.0 ml, DDW)

L-Carnitine helps transport fatty acids into cells to be used as energy, while the lipotropic compounds support fat metabolism and liver function, enhancing the overall fat-burning process

Crop maturity impacts pesticide uptake, where immature crops have greater residues since they have greater permeability, whereas mature crops have lesser residues because of metabolic hydrolysis (Kariyanna et al., 2024)