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Subsequent cell culture studies revealed that GSSG accumulation, as opposed to GSH reduction, sensitized hepatocytes to TNF killing by reducing the TNF-triggered NF-B activity

We found that compared to the untreated categories, treatment with 1/10 the MIC of PZA or 1/10 the MIC of INH resulted in a significant decrease in the burden of intracellular M

The authors suggested that high levels of mechanical stress and exposure to excess H2O2 interfere with the Smad/TGF-1 pathway, significantly altering ECM remodelling and promoting POP (Zhang et al