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Selective COX-2 inhibitors reduce gastrointestinal damage but may predispose patients to myocardial infarction and thrombosis by decreasing prostacyclin levels

20 of the General Thoracic Surgery Simultaneous Scientific Session

These gene products are responsible for a wide range of antioxidant, anti-inflammatory, cytoprotective, and detoxification functions and include catalase, superoxide dismutase (SOD)-3, heme oxygenase-1, glutathione-S-transferases, NAD(P)H-quinone oxidoreductase (NQO1), glutathione peroxidase, and glucuronosyltransferase-1a6 (UGT-1a6) [11]