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By combating oxidative stress and promoting cellular health, these ingredients help reduce the appearance of fine lines and wrinkles

Harold Lancer, a celebrity dermatologist in Los Angeles, added that it is generally considered more of a specialized, targeted ingredient that is typically found in advanced formulations and high-performance products

ERR target-gene expression (for example, Ppargc1a, Tfam, OXPHOS subunits), oxygen-consumption rate in cells, and, in vivo, indirect calorimetry parameters (energy expenditure, RER), plus mitochondrial DNA and cytochrome-c content in muscle

The Oxford 2011 levels of evidence