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Schmutzler C, Mentrup B, Schomburg L, Hoang-Vu C, Herzog V, Khrle J (2007) Selenoproteins of the thyroid gland: expression, localization and possible function of glutathione peroxidase 3

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Normally, the excess of ROS in the mitochondria is neutralized by the endogenous antioxidant system which comprises several enzymes and non-enzymatic antioxidants [100] including reduced glutathione (GSH), vitamins C, and E, the Cu/Zn-superoxide dismutase (SOD) in the cytoplasm, and Mn-SOD in the mitochondrial matrix, catalase in the peroxisomes, glutathione peroxidase (GSH-Px), etc