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The copper ion itself serves as a cofactor for lysyl oxidase, the enzyme responsible for collagen and elastin cross-linking, meaning GHK-Cu both stimulates production of new structural proteins and ensures they are properly stabilized

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GHK-Cu (glycyl-L-histidyl-L-lysine-copper) is a naturally occurring tripeptide - three amino acids bound to a copper ion

People taking certain common medications including metformin for blood sugar management and proton pump inhibitors for acid reflux also face increased deficiency risk