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While research is still emerging, some evidence and provider feedback suggest that adding B12 may decrease side effects like fatigue and nausea

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The peptide also appears to have some direct effects on peripheral tissues beyond the central nervous system, including potential metabolic effects, cardiovascular influences, and immunomodulatory properties

Gahl WA, Balog JZ, Kleta R (2007) Nephropathic cystinosis in adults: natural history and effects of oral cysteamine therapy