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However, as detailed above, cells that exhibit higher levels of mitochondrial activity are less sensitive to 5FU treatment, and those with compromised mitochondrial function are more sensitive, correlating with intrinsic resistance

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Yamamoto K, Ueno T, Kawaoka T, et al

Anagawa-Nakamura A, Ryoke K, Yasui Y, Shoda T, Sugai S

Nevertheless, the epigenetic network is intricate, and the recently discovered genes with differential expression may be just the tip of the iceberg in the context of ASD