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These results suggest that HOXA2 overexpression can reduce ER stress and oxidative stress in the kidneys of UUO mice

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Research on nanozymes in living organisms is expected to progress further, with promising applications in addressing redox imbalances, metabolic disorders, and immune dysfunctions

Figure 6E ), a key driver enzyme of ferroptotic lipid peroxidation, exhibits heterogeneous expression across different renal cell types and disease states, directly reflecting cell type-specific roles of lipid metabolism reprogramming in renal ferroptosis