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Given the complex interrelationships among NAD + metabolism, mitochondrial function, and redox homeostasis, the uncontrolled supplementation of these elements may paradoxically lead to the exacerbation of oxidative stress or the impairment of cellular balance in individuals who are predisposed to such conditions

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They are directly involved with the functioning of the nervous system, energy production, and the synthesis of different signaling molecules

Early diagnosis and treatment of RA can help control the disease and prevent lasting damage to joints and other structures