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9,10 Mitochondria, which are critical for cellular respiration and metabolism, suffer damage to their own mitochondrial DNA by the actions of reactive oxygen species and peroxynitrite compounds, and they have been directly implicated in the process leading to cessation of ATP synthesis

FOLIC ACID supplementation is highly recommended during pregnancy, as deficiencies in young growing animals are often associated with retardation

This process is considered an endogenous defense mechanism against ROS