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Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

Hippocampal GSK3 as a molecular link between obesity and depression

As oxidative stress increases, further stimulation of pro-inflammatory cytokines such as TNF- and IL-1 increases and contributes to synaptic dysfunction and neuronal degeneration ( These studies suggest that the loss of antioxidant defense is an early biochemical event rather than a late-stage consequence of neuronal death

This includes mood swings, irritability, headache, fatigue, constipation, abdominal cramping, anxiety, insomnia, and more [24]