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Elevated pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-), interleukin (IL)1, and IL-6 in patients with depression may disrupt emotional regulation by crossing the bloodbrain barrier [15], while depressive behaviors can further exacerbate inflammation [16]

Approximately 60% of patients who used combination therapy may suffer severe side effects, including autoimmune inflammation in the heart and the nervous system [14, 15]

BPC-157 is gaining attention as a powerful peptide with a wide range of potential benefits

Its sequence contains two acidic residues glutamic acid and aspartic acid giving the molecule a net negative charge at physiological pH