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Although the research did not give a physiological explanation for the results, Silverstein said that since nicotine and smoking harm the vascular system, the study suggests they also damage blood vessels and neurons in the retina

Taking these studies together we hypothesise that stressful conditions imposed by CS induces cellular stress responses in both host and microbial cells permitting adaptation to harsh conditions with the net effect of increasing virulence and/or potential for infection

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