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Its the addictive substance thats found in both cigarettes and e-cigarettes, but it doesnt contribute to your calorie count

Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids

Yet smoking still kills 1 in 5 Americans, or 440,000 people a year, the Centers for Disease Control and Prevention says

And I think that's a perfect example of why it's so important to really do the best we can to try and get to either adjustment for confounding, or doing these kinds of studies like the Mendelian randomisation analysis, to get at whether or not these associations are causal