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Diacetyl is banned as a flavouring for e-liquids in Europe, and there are varying levels of toleration for THC in Europe - these reasons may explain why recorded instances of EVALI in Europe are almost non-existent

According to the Federal Trade Commission (FTC), the four major cigarette manufacturers sold 800 million more cigarettes in the United States in 2020 than the previous year, or 203.7 billion units.[1]Chewing tobacco sales also increased slightly, while e-cigarette sales, measured by other sources, declined for the first time

Human primary bronchial epithelial cells (PBEC) and representative human type II alveolar cells cultured at airliquid interface (ALI) were used to develop physiologically relevant bronchial- (bro-ALI) and alveolar mucosa (alv-ALI) models for assessing the molecular effects of E-smoke exposure