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withdrawal: anxiety, insomnia, tremor, seizures potentially life-threatening Cocaine/Stimulants (F14/F15): Tachycardia, hypertension, dilated pupils, paranoia, nasal septum perforation (cocaine), hyperthermia

Our sample is large (734 CHR individuals, from an initial pool of 1,012 participants including controls) and drawn from eight sites across North America, enhancing generalizability

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[28] State Options to Prevent and Reduce Cigarette Smuggling and Tax Evasion And Block Other Illegal State Tobacco Tax Evasion. Campaign for Tobacco-Free Kids