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This was Nicotiana rustica whats called mapacho in the northern Amazon and the main ingredient of the tobacco snuff known as rap (pronounced ha-peh) found in the southern Amazon

Archived from the original on 15 March 2016

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Methods: Developed in MATLAB version 9.2, the model consisted of a transition sub-model, which simulated annual changes in product use based on national survey data and Test Product-specific studies, and a mortality sub-model, which linked survival outcomes to product transitions using an excess relative risk estimate of 5% for the Test Product relative to cigarettes