minimum age for tobacco purchases An incredible public health advance': Raising the legal to purchase Legal smoking age - Wikipedia

at least $289 billion each year, including at least $151 billion in lost productivity and $130 billion in direct healthcare expenditures

To investigate the putative genetic basis of this disease, we generated high-quality whole-genome data from 249 individuals spanning the species range, including New Zealand mainland (Northern range) and sub-Antarctic Enderby (Auckland Islands) and Campbell Islands (Southern range)

So they're not completely risk-free

"Together they show that the epidemic of disease and death caused by cigarette smoking increases progressively over many decades, peaking 50 or more years after the widespread uptake of smoking in adolescence