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In vitro studies suggest that exposure to TB-500 may support cell movement and structural coordination, and may also participate in signaling pathways linked to angiogenesis and modulation of inflammatory mediators

J Physiol Pharmacol 55:595606 Ercal N, Aykin-Burns N, Gurer-Orhan H, Mcdonald JD (2002) Oxidative stress in a phenylketonuria animal model

This clearance mechanism is essential for maintaining redox balance, as the accumulation of protein aggregates can enhance mitochondrial dysfunction and promote excessive generation of ROS, creating a pro-oxidative and inflammatory environment