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Having high blood pressure or Type 2 diabetes both known to impair cognitive performance didn't change the relationship researchers found between greater levels of nicotine byproducts in the blood and lower cognitive test scores, suggesting smoking independently harms brain function

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However, more specific studies focused on vaping are needed, as vaping lacks the tar and numerous chemicals found in cigarettes that could impact migraine triggers

Monteith concluded, in a statement from the American Academy of Neurology, which publishes the journal, "While this investigation of migraine and vascular events in older people found that only smokers with migraine have an increased risk of stroke, earlier studies have shown that women younger than 45 who have migraine with aura are also at an increased risk of stroke, whether or not they smoke." In 2010 researchers determined that people who suffer migraines are about twice as likely as people without the painful headaches to suffer a stroke caused by a blood clot