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Expired nicotine pouches do not turn unsafe and do not cause side effects

This versatility contributed to the production of tabako-ire in large numbers and an extraordinary diversity of styles

Although concordances between both tests were relatively high, FTND test should be considered the best option for screening of nicotine dependence since it has a better performance on both sexes

It is important to acknowledge that the early phase of the atherosclerotic process is characterized by ED, whereas the later phases result in arterial stiffness, a marker that also reflects vascular NO bioavailability and associates with risk of cardiovascular events [55]