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2.3.1 Curcumin Curcumin, the principal polyphenol from Curcuma longa, suppresses PsO-related inflammation by inhibiting IB kinase, thereby preventing NF-B activation and downstream cytokine transcription [40] In murine imiquimod (IMQ) models, curcumin reduces epidermal hyperplasia and attenuates IL-17 and IL-23 signaling

Lim SH, Morris A, Li K, Fitch AC, Fast L, Goldberg L, Quesenberry M, Sprinz P, Meth B (2018) Intestinal microbiome analysis revealed dysbiosis in sickle cell disease

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