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Choline an essential nutrient required for phosphatidylcholine synthesis, which is genuinely necessary for VLDL assembly and hepatic fat export

However, in individuals with normal B12 status, additional supplementation does not enhance metabolic rate or promote fat oxidation

Higher Bioavailability : Injections provide higher bioavailability of B12 because the vitamin is delivered directly to the bloodstream, ensuring maximum absorption

PAS is supporting research to explore more flexible and less resource-intensive methods, including: Self-Administration : Advocating for more patients (if they are willing) to be taught how to administer their own injections safely at home, reducing reliance on GP appointments