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Drummond MB, Upson D

The nondrinker subgroup had the smallest sample size of the subgroups, so replication in larger samples is needed before firm conclusions may be drawn about whether drinking status should be taken into account when considering naltrexone as an adjunct smoking cessation treatment in patients who have not responded to approved first-line pharmacotherapies

Any tobacco use, including e-cigarettes, is a health threat, particularly to young people. Related: E-Cigarettes Deliver Harmful Chemicals E-cigarettes are now the most commonly used tobacco product among children, teens and young adults

Moreover, the data depends on self-reports, which may underestimate smoking prevalence