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To understand mediators of cagrilintide action, we generated a transcriptomics atlas of over 530,000 cells comprising 80 neuronal cell populations across rat, mouse and macaque caudal brainstem, with spatial profiling to map distribution in the rat dorsal vagal complex (DVC)

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(2022), the clinical trial with oral administration of FMT capsules in depressed irritable bowel syndrome (IBS) patients enhanced bacterial alpha diversity and increased the abundance of bacterial communities predominantly Bacteroides immitis and Bacteroides thicketi , as well as an attestation to significant improvement in depressive symptoms