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Notably, among these cytokines, IFN- and IL-6 hold pivotal roles in RA inflammation [23] TNF- and IL-6 play a vital role in the progression of RA by elevating the expression of adhesion molecules on the endothelial cells found in synovial venules [24]

Another comparative study (53) with mildly dyslipidemic patients reached similar results, finding a decrease in the production of thromboxane B2 and an increase in plasma anti-oxidant capacity after consumption of HOTYR contained in extra virgin olive oil (166 mg/l

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