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Government regulations and increased taxation on cigarettes also may be leading young adults to embrace alternative methods of tobacco consumption
and Slotkin, T.A., "Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macromolecules," Brain Res
Studies distinguishing between e-cigarettes with and without nicotine found increases in endothelial progenitor cells, endothelial vesicles, plasma myeloperoxidase, arterial stiffness, changes in nicotine receptors, alveolar macrophages, and mononuclear phagocytes, leading to altered inflammatory responses and increased pulmonary susceptibility in users of nicotine-containing e-cigarettes (29, 41, 46)