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NAD + is reduced by 70% within 3 to 24 months, and as a compensation, the concentration of NADH has increased by 50%

[DOI] [PubMed] [Google Scholar] 106.Greco F., Liguori A., Sindona G., Uccella N

A recent study found that genetic DAO deficiency contributed to histamine intolerance in 79% of patients.[ref] (Members will see their DAO genotypes below in the genotype report.) Historical note: Excess histamine is the cause of scombroid poisoning a type of food poisoning that occurs after consuming fish that is not fresh

J Cereb Blood Flow Metab 18(6):6105 Meier TB, Savitz J (2022) The kynurenine pathway in traumatic brain injury: implications for psychiatric outcomes