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Nicotine is highly addictive, and regular use, regardless of frequency, can result in dependence

It also matters how fast you smoke

Barbara Stanwyck Beginning her smoking habit at the remarkably young age of nine years old , Barbara Stanwyck developed a lifelong relationship with nicotine that originated in Broadways chorus lines

cardiovascular effects of cigarettes and e-cigarettes are strikingly similar, and these harmful effects on blood vessel function are likely caused by airway irritation due to inhalation of a foreign substance, rather than a specific component of the cigarette smoke or e-cigarette vapor (aerosol) (ATVB)