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Increasing the internal resistance can limit the the ability to provide current. If you look at better quality batteries they will give you a continuous C ratting and a Maximum burst C rating

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Its not that the system is overreacting to exercise its quite the opposite its simply not responding which suggests that the muscle repair and antioxidants and whatever other systems that should be ramping up to ameliorate and heal are on vacation in ME/CFS

Clinical research suggested doses in the range of 1-10mcg per kilogram of body weight showed efficacy, though most protocols standardized around 4-6mcg/kg for practical application