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This synthetic peptide mimics EPOs tissue-protective properties by specifically binding to the innate repair receptor (IRR), a distinct receptor complex that mediates cytoprotective and anti-inflammatory effects

Two randomized, placebo-controlled clinical trials were conducted at separate clinical centers using consistent protocols for medication, injection method (periodontal tissue injection), inclusion and exclusion criteria, and outcome assessments

These signaling pathways influence endothelial cell communication, angiogenic responses, and cellular survival under oxidative stress conditions

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