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It is worth noting that nicotine sourcing varies between brands

The TNCO values that are determined in the test therefore do not provide an insight into the harmfulness for smokers

Discussion Many governments in Europe have favoured more restrictive policies with respect to illicit drugs than for alcohol or tobacco, on the grounds that they regard both illicit drug abuse and related problems as a significantly larger problem for society 58

We note that this strategy only works when taxes on combustible products are significant enough to both discourage youth uptake and to encourage smokers to switch to less harmful products