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The specific diagnosis of G6PD deficiency is made by adding a measured amount of hemolysate to an assay mixture containing substrate (glucose-6-phosphate) and cofactor (NADP) and then spectrophotometrically measuring the rate of NADPH generation

In recent years, ROS have gained more attention, because of their central role in the progression of many inflammatory diseases [2]

The histomorphological changes in hepatotoxic liver enlargement without enzyme induction include fluid accumulation, fatty change in hepatocytes, inflammatory cell infiltration, fibrosis, and possibly granuloma formation (Glaister 1986

P., and Gluud, C