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A second comparison is with the N-terminal copper-binding site of human serum albumin, which uses the sequence Asp-Ala-His-Lys (DAHK) at the N-terminus of the albumin protein to bind copper(II) through the same general N-terminal/histidine/amide-nitrogen coordination geometry

In: Targeted Therapy of Acute Myeloid Leukemia, 2015

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These changes in gross mechanical properties following estrogen treatment correlate with specific beneficial changes at the histological level