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Keywords: peripheral nerve, neurofibroma, schwannoma, perineurioma, MPNST Introduction Peripheral nerve sheath tumors encompass a spectrum of well defined clinicopathologic entities [87], ranging from benign tumors, such as schwannoma, to high grade malignant neoplasms termed malignant peripheral nerve sheath tumors (MPNST)(Table 1), which are often resistant to conventional treatments[126]