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As a result, GLP- 1's primary effects include decreasing body weight, protecting against cardiovascular disease, and lowering fasting and postprandial blood glucose levelsall of which are therapeutic targets in T2DM

CJC-1295 is a long-acting analogue of growth hormone-releasing hormone (GHRH), while Ipamorelin is a selective ghrelin receptor agonist

TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter

Notably, thioredoxin reductase (TrxR) can reduce oxidized forms of glutaredoxins (Grx) and GPx, both of which depend on GSH for their redox activity [44]