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The PAM-dependent responses to green bean coffee were three-fold greater than those to dark roasted coffee, consistent with 7 receptor activation by choline, a component of coffee that is partially degraded in the roasting process

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Respondents were further excluded if they were missing data on sexual orientation and gender identity (n=40 respondents excluded) or age and race/ethnicity (n=51 excluded), for a final analysis sample of 12,615 youth (71.8% of all respondents who initiated the survey), from all 50 states and Washington, DC

Many said they didnt know the pods contained nicotine