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However, these arguments were refuted by the extensive review of the current evidence conducted by the National Cancer Institute, which concluded that industrys marketing significantly impacted tobacco initiation among youths, discouraged quitting, and increased product demand among some established users (National Cancer Institute, 2008)

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The increasing disease burden attributable to current smoking, particularly in low- and middle-income countries 4 , demonstrates the relevance of the present study, which quantifies the strength of the evidence using an objective, quantitative, comprehensive and comparative framework