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Accessed 27 Jan 2017 Royal College of Physicians (2016) Nicotine without smoke: tobacco harm reduction

or One trial of bupropion or nortriptyline Other Special Authority approval criteria include that patients should be enrolled in (or about to enrol in) a smoking cessation programme which includes prescriber or nurse monitoring, must not have used varenicline in the previous six months, and that it is not being used in combination with other smoking cessation medicines

I have attached information on younger adult purchase patterns and target outlets for DB, wrote one RJ Reynolds tobacco executive to another in 1984, about Project DB, a marketing effort targeting younger purchasers