5,41 In addition, its reduced form, NADPH, is essential for diminishing ROS levels
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Inhibitors targeting enzymes such as adenosine phosphate transferase, non-ribosomal peptide synthase (NRPS), polyketide synthase, and NRPS-independent siderophore synthases impair microbial iron uptake and enhance host-mediated clearance (Petrik et al., 2012
Compared with large biologic medicines such as monoclonal antibodies, they are often smaller and sometimes easier to synthesize or modify