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One example where NO influences oxidative/nitrosative stress functioning as antioxidant could be related to enzymatic inhibition of the ROS producing enzymes NADPH oxidases probably via protein nitrosylation followed by loss of the heme prosthetic group [41]

Cell Stem Cell 28 , 15821596.e6 (2021)

While cross-species analyses are commonly used to explore shared biological mechanisms, it is important to recognise that mice and humans have differences in gene expression, metabolism and bone biology