When a compound average effect is only 2 kilograms over 12 weeks, many individual participants likely saw minimal to no change, while a smaller subset may have responded more strongly, pulling the average up
Many cardiovascular risk factors such as diabetes mellitus, hypertension and hyperlipidemia are demonstrated to stimulate the interaction of Cav-1 and eNOS, reduce nitric oxide production resulting in endothelial dysfunction and subsequently the formation of atherosclerotic lesion 41,42,43
The result, for many people, is a chronic lower-level insufficiency that does not produce clinical deficiency symptoms but nonetheless affects the quality of immune response, skin health, collagen production and overall cellular resilience
They are not screening for experimental tissue-repair compounds